Nucleic acid-induced inflammation on hematopoietic stem cells

•Nucleic acid-sensing inflammatory pathways affect developmental and adult hematopoiesis.•RNA and DNA sensing pathways are essential for sensing exogenous and endogenous nucleic acids.•The majority of RNA and DNA sensing pathways activate a type I IFN response and NF-κB signaling pathways.•Disruptio...

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Veröffentlicht in:	Experimental hematology 2024-03, Vol.131, p.104148-104148, Article 104148
Hauptverfasser:	Vu, Giang To, Awad, Valerie, Norberto, Maria Feliz, Bowman, Teresa V., Trompouki, Eirini
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Bone Marrow Hematopoiesis - physiology Hematopoietic Stem Cells - metabolism Humans Inflammation - metabolism Nucleic Acids - metabolism
Online-Zugang:	Volltext
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