Anti–Phospholipase A2 Receptor 1 and Anti–Cysteine Rich Antibodies, Domain Recognition and Rituximab Efficacy in Membranous Nephropathy: A Prospective Cohort Study

Proteinuria and anti–phospholipase A2 receptor 1 (anti-PLA2R1) antibody titers are associated with primary membranous nephropathy (MN) outcomes. We evaluated the association of antibodies against the cysteine-rich (CysR) and C-type lectin 1, 7, and 8 (CTLD1, CTLD7, and CTLD8) domains of PLA2R1 with...

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Veröffentlicht in:	American journal of kidney diseases 2024-05, Vol.83 (5), p.588-600.e1
Hauptverfasser:	Ruggenenti, Piero, Reinhard, Linda, Ruggiero, Barbara, Perna, Annalisa, Perico, Luca, Peracchi, Tobia, Fidone, Diego, Gennarini, Alessia, Benigni, Ariela, Cortinovis, Monica, Hoxha, Elion, Remuzzi, Giuseppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Autoantibodies - blood Autoantibodies - immunology Cohort Studies CysR Cysteine domain recognition Female Glomerulonephritis, Membranous - drug therapy Glomerulonephritis, Membranous - immunology Humans Immunologic Factors - therapeutic use Male membranous nephropathy Middle Aged nephrotic syndrome PLA2R1 Prospective Studies Proteinuria - drug therapy Receptors, Phospholipase A2 - immunology rituximab Rituximab - therapeutic use sex Treatment Outcome
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