Real-world effectiveness and predictors of super-responders to dupilumab in a Chinese uncontrolled asthma cohort

Background: Dupilumab has been shown to be effective in clinical trials for moderate-to-severe uncontrolled asthma. However, the efficacy of dupilumab in the real world and the prediction of treatment response have not been well studied in patients with asthma. Objective: To investigate the efficacy...

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Veröffentlicht in:	Allergy and asthma proceedings 2024-01, Vol.45 (1), p.e14-e22
Hauptverfasser:	Chen, Xiaoying, Luo, Huiting, Yan, Wenbo, Tang, Kailun, Huang, Junfeng, Xie, Shuojia, Lin, Zhenxuan, Zhang, Zhenle, Shi, Xu, Xian, Mo, Wang, Wanjun, Li, Jing, Chen, Ruchong
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Asthma Biologics Biomarkers Blood Clinical trials Confidence intervals Corticoids Corticosteroids Dupilumab Effectiveness Efficacy Eosinophils Inflammation Leukocytes (eosinophilic) Lungs Monoclonal antibodies Multivariable control Nitric oxide Patients Prediction Prediction models Prednisone Real-World Respiratory function Sputum Super-Responders
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