Chlorogenic Acid Attenuates Hepatic Steatosis by Suppressing ZFP30

Nonalcoholic fatty liver disease (NAFLD) has become a major global health problem with no approved pharmacological treatment for this disease. Thus, it is urgent to develop effective therapeutic targets for clinical intervention. Here, we show for the first time that ZFP30, a member of the KRAB-ZFP...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2024-01, Vol.72 (1), p.245-258
Hauptverfasser:	Ding, Han, Ge, Kunyi, Fan, Changyu, Liu, Dandan, Wu, Chenyu, Li, Rongpeng, Yan, Feng-Juan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioactive Constituents, Metabolites, and Functions Chlorogenic Acid - metabolism Chlorogenic Acid - pharmacology Diet, High-Fat Fatty Acids, Nonesterified - metabolism Humans Lipid Metabolism Liver - metabolism Mice Mice, Inbred C57BL Non-alcoholic Fatty Liver Disease - drug therapy Non-alcoholic Fatty Liver Disease - genetics Non-alcoholic Fatty Liver Disease - metabolism PPAR alpha - genetics PPAR alpha - metabolism
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