The deposition of lanthanum carbonate may activate macrophages to induce gastrointestinal mucosal injury in patients with chronic kidney disease: an in vitro caco-2/THP-1 macrophage coculture model study

The aim of this study was to investigate the effect and possible underlying mechanism of La 2 (CO 3 ) 3 deposition on GI mucosal inflammation. Our results showed that La 2 (CO 3 ) 3 can dissolve in artificial gastric fluids and form lanthanum phosphate (LaPO 4 ) precipitates with an average size of...

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Veröffentlicht in:	Journal of biological inorganic chemistry 2024-02, Vol.29 (1), p.101-112
Hauptverfasser:	Song, Ya-Ju, Liu, Hui-Xue, Yang, Xiao-Gai
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Electrical resistivity Epithelial cells Epithelium Inflammation Interleukin 8 Intestine Kidney diseases Lanthanum Life Sciences Macrophages Microbiology Mucosa Original Paper
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