Secretagogue effect of PDE4 inhibitor apremilast on human salivary gland organoids obtained from primary Sjögren's syndrome patients

The aim of the study was to culture vital salivary gland organoids obtained through labial or parotid biopsy of primary Sjögren's syndrome (pSS) patients in order to evaluate their morphological and functional features in basal condition and after stimulation with Cystic Fibrosis Transmembrane...

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Veröffentlicht in:Clinical and experimental rheumatology 2023-12, Vol.41 (12), p.2493-2501
Hauptverfasser: Manfrè, Valeria, Parisi, Salvatore, Caligiuri, Isabella, Repetto, Ombretta, Zabotti, Alen, Pegolo, Enrico, Fabro, Cinzia, De Vita, Salvatore, Canzonieri, Vincenzo, Di Loreto, Carla, Rizzolio, Flavio, Quartuccio, Luca
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Sprache:eng
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