Evaluating the Protective Effects of Melatonin Against Chronic Iron Administration in Male Wistar Rats: a Comparative Analysis of Affective, Cognitive, and Oxidative Stress with EDTA Chelator

Iron is the dominant metal in the brain and is distributed widely. However, it can lead to various neuropathological and neurobehavioral abnormalities as well as oxidative stress. On the other hand, melatonin, a pineal hormone, is known for its neuroprotective properties, as well as its ability to a...

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Veröffentlicht in:	Biological trace element research 2024-10, Vol.202 (10), p.4531-4546
Hauptverfasser:	Rezqaoui, Ayoub, Boumlah, Soufiane, El Hessni, Aboubaker, El Brouzi, Mohamed Yassine, El Hamzaoui, Abdelghafour, Ibouzine-dine, Laila, Benkirane, Samir, Adnani, Manal, Mesfioui, Abdelhalem
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Animals Antidepressants Anxiety Anxiety - chemically induced Anxiety - prevention & control Biochemistry Biological stress Biomedical and Life Sciences Biotechnology Catalase Chelating agents Chronic exposure Cognition - drug effects Cognitive ability Comparative analysis Edetic acid Edetic Acid - pharmacology Ethylenediaminetetraacetic acids Heavy metals Hippocampus Hippocampus - drug effects Hippocampus - metabolism Hormones Impairment Iron Iron - metabolism Iron sulfates Life Sciences Lipid peroxidation Lipids Male Males Melatonin Melatonin - administration & dosage Melatonin - pharmacology Neuroprotection Nitric oxide Nutrition Oncology Oxidative stress Oxidative Stress - drug effects Peroxidation Pineal gland Prefrontal cortex Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Rats Rats, Wistar Sodium chloride Sulfates
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