Female-specific pancreatic cancer survival from CT imaging of visceral fat implicates glutathione metabolism in solid tumors

To identify if body composition, assessed with preoperative CT-based visceral fat ratio quantification as well as tumor metabolic gene expression, predicts sex-dependent overall survival (OS) in patients with pancreatic ductal adenocarcinoma (PDAC). This was a retrospective analysis of preoperative...

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Veröffentlicht in:	Academic radiology 2024-06, Vol.31 (6), p.2312-2323
Hauptverfasser:	Ballard, David H., Nguyen, Gerard K., Atagu, Norman, Camps, Garrett, Salter, Amber, Jaswal, Shama, Naeem, Muhammad, Ludwig, Daniel R., Mellnick, Vincent M., Peterson, Linda R., Hawkins, William G., Fields, Ryan C., Luo, Jingqin, Ippolito, Joseph E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Pancreatic Ductal - diagnostic imaging Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - metabolism Female Glutathione - metabolism Humans Intra-Abdominal Fat - diagnostic imaging Intra-Abdominal Fat - metabolism Male Metabolism Middle Aged Pancreatic cancer Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Retrospective Studies Sex differences Sex Factors Survival Rate Tomography, X-Ray Computed - methods Visceral fat
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