Biomechanical response of ultrathin slices of hypertrophic cardiomyopathy tissue to myosin modulator mavacamten

Hypertrophic cardiomyopathy (HCM) is the most common inherited myocardial disorder of the heart, but effective treatment options remain limited. Mavacamten, a direct myosin modulator, has been presented as novel pharmacological therapy for HCM. The aim of this study was to analyze the biomechanical...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2024-01, Vol.170, p.116036-116036, Article 116036
Hauptverfasser:	Amesz, Jorik H., Langmuur, Sanne J.J., Zhang, Lu, Manintveld, Olivier C., Schinkel, Arend F.L., de Jong, Peter L., de Groot, Natasja M.S., Taverne, Yannick J.H.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Hypertrophic cardiomyopathy Living myocardial slices Myosin modulators Translational research
Online-Zugang:	Volltext
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