Tissue factor binds to and inhibits interferon-α receptor 1 signaling

Tissue factor (TF), which is a member of the cytokine receptor family, promotes coagulation and coagulation-dependent inflammation. TF also exerts protective effects through unknown mechanisms. Here, we showed that TF bound to interferon-α receptor 1 (IFNAR1) and antagonized its signaling, preventin...

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Veröffentlicht in:Immunity (Cambridge, Mass.) Mass.), 2024-01, Vol.57 (1), p.68-85.e11
Hauptverfasser: Manoharan, Jayakumar, Rana, Rajiv, Kuenze, Georg, Gupta, Dheerendra, Elwakiel, Ahmed, Ambreen, Saira, Wang, Hongjie, Banerjee, Kuheli, Zimmermann, Silke, Singh, Kunal, Gupta, Anubhuti, Fatima, Sameen, Kretschmer, Stefanie, Schaefer, Liliana, Zeng-Brouwers, Jinyang, Schwab, Constantin, Al-Dabet, Moh'd Mohanad, Gadi, Ihsan, Altmann, Heidi, Koch, Thea, Poitz, David M, Baber, Ronny, Kohli, Shrey, Shahzad, Khurrum, Geffers, Robert, Lee-Kirsch, Min Ae, Kalinke, Ulrich, Meiler, Jens, Mackman, Nigel, Isermann, Berend
Format: Artikel
Sprache:eng
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