Ameliorative effects of androstenediol against acetic acid-induced colitis in male wistar rats via inhibiting TLR4-mediated PI3K/Akt and NF-κB pathways through estrogen receptor β activation

5-androstenediol (ADIOL) functions as a selective estrogen receptor β (ERβ) ligand with a protective effect against many diseases. So, we conducted a novel insight into its role in acetic acid (AA)-induced colitis and investigated its effect on TLR4-Mediated PI3K/Akt and NF-κB Pathways and the poten...

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Veröffentlicht in:International immunopharmacology 2024-01, Vol.127, p.111414-111414, Article 111414
Hauptverfasser: Hassan, Heba A, Mohamed Abdelhamid, Amira, Samy, Walaa, Osama Mohammed, Heba, Mortada Mahmoud, Samar, Fawzy Abdel Mageed, Amal, Abbas, Noha A T
Format: Artikel
Sprache:eng
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