The inhibition of FTO attenuates the antifibrotic effect of leonurine in rat cardiac fibroblasts

Myocardial fibrosis (MF) is a common pathological condition in cardiovascular diseases that often causes severe cardiac dysfunction. MF is characterized by changes in cardiomyocytes, cardiac fibroblasts (CFs), levels of collagen (Col) -1, -3, and overdeposition of the extracellular matrix. Our previ...

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Veröffentlicht in:Biochemical and biophysical research communications 2024-01, Vol.693, p.149375, Article 149375
Hauptverfasser: Meng, Yuwei, Xi, Tianlan, Fan, Jun, Yang, Qiyu, Ouyang, Jing, Yang, Jiadan
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Sprache:eng
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