Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3
MST1, MST2, MST3, MST4, and YSK1 are conserved members of the mammalian sterile 20-like serine/threonine (MST) family that regulate cellular functions such as proliferation and migration. The MST3 isozyme plays a role in regulating cell growth and apoptosis, and its dysregulation has been linked to...
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Veröffentlicht in: | Journal of medicinal chemistry 2024-01, Vol.67 (1), p.674-690 |
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Hauptverfasser: | , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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