Ferroptosis-related gene glutathione peroxidase 4 promotes reprogramming of glucose metabolism via Akt–mTOR axis in intrahepatic cholangiocarcinoma

Abstract The role of the ferroptosis-related gene glutathione peroxidase 4 (GPX4) in oncology has been extensively investigated. However, the clinical implications of GPX4 in patients with intrahepatic cholangiocarcinoma (ICC) remain unknown. This study aimed to evaluate the prognostic impact of GPX...

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Veröffentlicht in:	Carcinogenesis (New York) 2024-03, Vol.45 (3), p.119-130
Hauptverfasser:	Hori, Yutaro, Yoh, Tomoaki, Nishino, Hiroto, Okura, Keisuke, Kurimoto, Makoto, Takamatsu, Yuichi, Satoh, Motohiko, Nishio, Takahiro, Koyama, Yukinori, Ishii, Takamichi, Iwaisako, Keiko, Seo, Satoru, Hatano, Etsuro
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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