Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) exert anti-inflammatory effects relevant to the chronic complications of type 2 diabetes. Although GLP-1RAs attenuate T cell-mediated gut and systemic inflammation directly through the gut intraepithelial lymphocyte GLP-1R, how GLP-1RAs inhibit sy...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell metabolism 2024-01, Vol.36 (1), p.130-143.e5
Hauptverfasser:	Wong, Chi Kin, McLean, Brent A., Baggio, Laurie L., Koehler, Jacqueline A., Hammoud, Rola, Rittig, Nikolaj, Yabut, Julian M., Seeley, Randy J., Brown, Theodore J., Drucker, Daniel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	autonomic nervous system diabetes Diabetes Mellitus, Type 2 Exenatide G protein-coupled receptor Glucagon-Like Peptide 1 - metabolism Glucagon-Like Peptide-1 Receptor - metabolism glucagon-like peptides gut-brain axis Humans immune Inflammation obesity Peptides - pharmacology Sepsis Toll-Like Receptor Agonists Tumor Necrosis Factor-alpha Venoms - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!