Discovery of a novel pyroptosis inhibitor acting though modulating glutathionylation to suppress NLRP3-related signal pathway

Pyroptosis is a proinflammatory type of regulated cell death and has been involved in many pathological processes. Inhibition of pyroptosis is thought to be a promising strategy for the treatment of related diseases. Here, we performed a phenotypic screening against NLRP3-dependent pyroptosis and ob...

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Veröffentlicht in:International immunopharmacology 2024-01, Vol.127, p.111314-111314, Article 111314
Hauptverfasser: Zhou, Nenghua, Zhang, Yun, Jiao, Yan, Nan, Jinshan, Xia, Anjie, Mu, Bo, Lin, Guifeng, Li, Xun, Zhang, Shanshan, Yang, Shengyong, Li, Linli
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Sprache:eng
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