Validated spectrofluorimetric method for the determination of netilmicin based on its interaction with o‐phthalaldehyde/mercaptoethanol: Evaluation of the method's greenness
In this study, netilmicin (NTM) was selectively assessed in its dosage forms after a facile derivatization reaction. The proposed approach was based on the interaction between NTM and o‐phthalaldehyde/2‐mercaptoethanol (Roth's reagent). The reaction product was fluorometrically measured at λemi...
Gespeichert in:
| Veröffentlicht in: | Luminescence (Chichester, England) England), 2024-02, Vol.39 (2), p.n/a |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | n/a |
|---|---|
| container_issue | 2 |
| container_start_page | |
| container_title | Luminescence (Chichester, England) |
| container_volume | 39 |
| creator | Salem AlSalem, Huda Saad Binkadem, Mona Talal Al‐Goul, Soha Obaydo, Reem H. El Hamd, Mohamed A. Katamesh, Noha S. Abdel‐Lateef, Mohamed A. |
| description | In this study, netilmicin (NTM) was selectively assessed in its dosage forms after a facile derivatization reaction. The proposed approach was based on the interaction between NTM and o‐phthalaldehyde/2‐mercaptoethanol (Roth's reagent). The reaction product was fluorometrically measured at λemission of 434 nm after λexcitation of 338 nm. All reaction conditions for achieving the optimum fluorescence switch‐on activity were visualized and monitored. Moreover, the method was validated under ICH guidelines, and was linear over the range 30–210 ng/ml after plotting netilmicin concentrations against the corresponding fluorescence intensity values. In addition, the selectivity of the developed method was investigated against either the co‐formulated drug (dexamethasone) or a common ophthalmic drop excipient (benzalkonium chloride) without interference from either of them. Furthermore, the developed method was applied to assay netilmicin in various samples of pharmaceutical eye drops with good recovery. Finally, multicriteria greenness and whiteness metrics were used to evaluate the sustainability, greenness, and whiteness of the approach. The applied tools were the AGREE algorithm, the RGB 12 algorithm, and HEXAGON.
Spectrofluorimetric determination of netilmicin based on its interaction with o‐phthalaldehyde/2‐mercaptoethanol. |
| doi_str_mv | 10.1002/bio.4644 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2902973729</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2902973729</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3494-383a9f1d5877cd63cbf4ef0bc29e007a0d32b8ca9aa6b5ce2bf86d471908c6793</originalsourceid><addsrcrecordid>eNp1kcFqFTEUhgdRbK2CTyABF7qZNpPMTSbuaqm2UOhG3Q6Z5MRJySRjkrHcnY_QN-k7-STm9rZXKHR1DuHj-8P5q-ptgw8bjMnRYMNhy9r2WbXfrAipOWnp891OV3vVq5SuMMaMMfGy2qMd7hpG6H51-0M6q2UGjdIMKsdg3BKinSBHq1AZY9DIhIjyCEhDhjhZL7MNHgWDPGTrJqusR4NMRVKebU7I-gJKdYdd2zyi8PfPzTzmUTrpNIxrDUcTRCXnHEqE9MF9Qqe_pVt26k3eNv5DQj8jgPeQ0uvqhZEuwZv7eVB9_3L67eSsvrj8en5yfFEr2oq2ph2VwjR61XGuNKNqMC0YPCgiAGMusaZk6JQUUrJhpYAMpmO65Y3AnWJc0IPq49Y7x_BrgZT7ySYFzkkPYUk9EZgITjnZoO8foVdhib78rlC0KadmjP8XqhhSimD6uVxZxnXf4H5TYl9K7DclFvTdvXAZJtA78KG1AtRb4No6WD8p6j-fX94J_wG0EquG</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2931808667</pqid></control><display><type>article</type><title>Validated spectrofluorimetric method for the determination of netilmicin based on its interaction with o‐phthalaldehyde/mercaptoethanol: Evaluation of the method's greenness</title><source>Access via Wiley Online Library</source><creator>Salem AlSalem, Huda ; Saad Binkadem, Mona ; Talal Al‐Goul, Soha ; Obaydo, Reem H. ; El Hamd, Mohamed A. ; Katamesh, Noha S. ; Abdel‐Lateef, Mohamed A.</creator><creatorcontrib>Salem AlSalem, Huda ; Saad Binkadem, Mona ; Talal Al‐Goul, Soha ; Obaydo, Reem H. ; El Hamd, Mohamed A. ; Katamesh, Noha S. ; Abdel‐Lateef, Mohamed A.</creatorcontrib><description>In this study, netilmicin (NTM) was selectively assessed in its dosage forms after a facile derivatization reaction. The proposed approach was based on the interaction between NTM and o‐phthalaldehyde/2‐mercaptoethanol (Roth's reagent). The reaction product was fluorometrically measured at λemission of 434 nm after λexcitation of 338 nm. All reaction conditions for achieving the optimum fluorescence switch‐on activity were visualized and monitored. Moreover, the method was validated under ICH guidelines, and was linear over the range 30–210 ng/ml after plotting netilmicin concentrations against the corresponding fluorescence intensity values. In addition, the selectivity of the developed method was investigated against either the co‐formulated drug (dexamethasone) or a common ophthalmic drop excipient (benzalkonium chloride) without interference from either of them. Furthermore, the developed method was applied to assay netilmicin in various samples of pharmaceutical eye drops with good recovery. Finally, multicriteria greenness and whiteness metrics were used to evaluate the sustainability, greenness, and whiteness of the approach. The applied tools were the AGREE algorithm, the RGB 12 algorithm, and HEXAGON.
Spectrofluorimetric determination of netilmicin based on its interaction with o‐phthalaldehyde/2‐mercaptoethanol.</description><identifier>ISSN: 1522-7235</identifier><identifier>EISSN: 1522-7243</identifier><identifier>DOI: 10.1002/bio.4644</identifier><identifier>PMID: 38081623</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>2‐mercaptoethanol ; Algorithms ; Benzalkonium chloride ; Dexamethasone ; Evaluation ; Fluorescence ; Multiple criterion ; Netilmicin ; o‐phthalaldehyde ; Reaction products ; Reagents ; Roth's reaction</subject><ispartof>Luminescence (Chichester, England), 2024-02, Vol.39 (2), p.n/a</ispartof><rights>2023 John Wiley & Sons Ltd.</rights><rights>2024 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3494-383a9f1d5877cd63cbf4ef0bc29e007a0d32b8ca9aa6b5ce2bf86d471908c6793</citedby><cites>FETCH-LOGICAL-c3494-383a9f1d5877cd63cbf4ef0bc29e007a0d32b8ca9aa6b5ce2bf86d471908c6793</cites><orcidid>0000-0002-9774-0587 ; 0000-0002-3020-4966</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbio.4644$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbio.4644$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27928,27929,45578,45579</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38081623$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Salem AlSalem, Huda</creatorcontrib><creatorcontrib>Saad Binkadem, Mona</creatorcontrib><creatorcontrib>Talal Al‐Goul, Soha</creatorcontrib><creatorcontrib>Obaydo, Reem H.</creatorcontrib><creatorcontrib>El Hamd, Mohamed A.</creatorcontrib><creatorcontrib>Katamesh, Noha S.</creatorcontrib><creatorcontrib>Abdel‐Lateef, Mohamed A.</creatorcontrib><title>Validated spectrofluorimetric method for the determination of netilmicin based on its interaction with o‐phthalaldehyde/mercaptoethanol: Evaluation of the method's greenness</title><title>Luminescence (Chichester, England)</title><addtitle>Luminescence</addtitle><description>In this study, netilmicin (NTM) was selectively assessed in its dosage forms after a facile derivatization reaction. The proposed approach was based on the interaction between NTM and o‐phthalaldehyde/2‐mercaptoethanol (Roth's reagent). The reaction product was fluorometrically measured at λemission of 434 nm after λexcitation of 338 nm. All reaction conditions for achieving the optimum fluorescence switch‐on activity were visualized and monitored. Moreover, the method was validated under ICH guidelines, and was linear over the range 30–210 ng/ml after plotting netilmicin concentrations against the corresponding fluorescence intensity values. In addition, the selectivity of the developed method was investigated against either the co‐formulated drug (dexamethasone) or a common ophthalmic drop excipient (benzalkonium chloride) without interference from either of them. Furthermore, the developed method was applied to assay netilmicin in various samples of pharmaceutical eye drops with good recovery. Finally, multicriteria greenness and whiteness metrics were used to evaluate the sustainability, greenness, and whiteness of the approach. The applied tools were the AGREE algorithm, the RGB 12 algorithm, and HEXAGON.
Spectrofluorimetric determination of netilmicin based on its interaction with o‐phthalaldehyde/2‐mercaptoethanol.</description><subject>2‐mercaptoethanol</subject><subject>Algorithms</subject><subject>Benzalkonium chloride</subject><subject>Dexamethasone</subject><subject>Evaluation</subject><subject>Fluorescence</subject><subject>Multiple criterion</subject><subject>Netilmicin</subject><subject>o‐phthalaldehyde</subject><subject>Reaction products</subject><subject>Reagents</subject><subject>Roth's reaction</subject><issn>1522-7235</issn><issn>1522-7243</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp1kcFqFTEUhgdRbK2CTyABF7qZNpPMTSbuaqm2UOhG3Q6Z5MRJySRjkrHcnY_QN-k7-STm9rZXKHR1DuHj-8P5q-ptgw8bjMnRYMNhy9r2WbXfrAipOWnp891OV3vVq5SuMMaMMfGy2qMd7hpG6H51-0M6q2UGjdIMKsdg3BKinSBHq1AZY9DIhIjyCEhDhjhZL7MNHgWDPGTrJqusR4NMRVKebU7I-gJKdYdd2zyi8PfPzTzmUTrpNIxrDUcTRCXnHEqE9MF9Qqe_pVt26k3eNv5DQj8jgPeQ0uvqhZEuwZv7eVB9_3L67eSsvrj8en5yfFEr2oq2ph2VwjR61XGuNKNqMC0YPCgiAGMusaZk6JQUUrJhpYAMpmO65Y3AnWJc0IPq49Y7x_BrgZT7ySYFzkkPYUk9EZgITjnZoO8foVdhib78rlC0KadmjP8XqhhSimD6uVxZxnXf4H5TYl9K7DclFvTdvXAZJtA78KG1AtRb4No6WD8p6j-fX94J_wG0EquG</recordid><startdate>202402</startdate><enddate>202402</enddate><creator>Salem AlSalem, Huda</creator><creator>Saad Binkadem, Mona</creator><creator>Talal Al‐Goul, Soha</creator><creator>Obaydo, Reem H.</creator><creator>El Hamd, Mohamed A.</creator><creator>Katamesh, Noha S.</creator><creator>Abdel‐Lateef, Mohamed A.</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QP</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>7U7</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F1W</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H95</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L.G</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9774-0587</orcidid><orcidid>https://orcid.org/0000-0002-3020-4966</orcidid></search><sort><creationdate>202402</creationdate><title>Validated spectrofluorimetric method for the determination of netilmicin based on its interaction with o‐phthalaldehyde/mercaptoethanol: Evaluation of the method's greenness</title><author>Salem AlSalem, Huda ; Saad Binkadem, Mona ; Talal Al‐Goul, Soha ; Obaydo, Reem H. ; El Hamd, Mohamed A. ; Katamesh, Noha S. ; Abdel‐Lateef, Mohamed A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3494-383a9f1d5877cd63cbf4ef0bc29e007a0d32b8ca9aa6b5ce2bf86d471908c6793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>2‐mercaptoethanol</topic><topic>Algorithms</topic><topic>Benzalkonium chloride</topic><topic>Dexamethasone</topic><topic>Evaluation</topic><topic>Fluorescence</topic><topic>Multiple criterion</topic><topic>Netilmicin</topic><topic>o‐phthalaldehyde</topic><topic>Reaction products</topic><topic>Reagents</topic><topic>Roth's reaction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Salem AlSalem, Huda</creatorcontrib><creatorcontrib>Saad Binkadem, Mona</creatorcontrib><creatorcontrib>Talal Al‐Goul, Soha</creatorcontrib><creatorcontrib>Obaydo, Reem H.</creatorcontrib><creatorcontrib>El Hamd, Mohamed A.</creatorcontrib><creatorcontrib>Katamesh, Noha S.</creatorcontrib><creatorcontrib>Abdel‐Lateef, Mohamed A.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Toxicology Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Luminescence (Chichester, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Salem AlSalem, Huda</au><au>Saad Binkadem, Mona</au><au>Talal Al‐Goul, Soha</au><au>Obaydo, Reem H.</au><au>El Hamd, Mohamed A.</au><au>Katamesh, Noha S.</au><au>Abdel‐Lateef, Mohamed A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Validated spectrofluorimetric method for the determination of netilmicin based on its interaction with o‐phthalaldehyde/mercaptoethanol: Evaluation of the method's greenness</atitle><jtitle>Luminescence (Chichester, England)</jtitle><addtitle>Luminescence</addtitle><date>2024-02</date><risdate>2024</risdate><volume>39</volume><issue>2</issue><epage>n/a</epage><issn>1522-7235</issn><eissn>1522-7243</eissn><abstract>In this study, netilmicin (NTM) was selectively assessed in its dosage forms after a facile derivatization reaction. The proposed approach was based on the interaction between NTM and o‐phthalaldehyde/2‐mercaptoethanol (Roth's reagent). The reaction product was fluorometrically measured at λemission of 434 nm after λexcitation of 338 nm. All reaction conditions for achieving the optimum fluorescence switch‐on activity were visualized and monitored. Moreover, the method was validated under ICH guidelines, and was linear over the range 30–210 ng/ml after plotting netilmicin concentrations against the corresponding fluorescence intensity values. In addition, the selectivity of the developed method was investigated against either the co‐formulated drug (dexamethasone) or a common ophthalmic drop excipient (benzalkonium chloride) without interference from either of them. Furthermore, the developed method was applied to assay netilmicin in various samples of pharmaceutical eye drops with good recovery. Finally, multicriteria greenness and whiteness metrics were used to evaluate the sustainability, greenness, and whiteness of the approach. The applied tools were the AGREE algorithm, the RGB 12 algorithm, and HEXAGON.
Spectrofluorimetric determination of netilmicin based on its interaction with o‐phthalaldehyde/2‐mercaptoethanol.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>38081623</pmid><doi>10.1002/bio.4644</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-9774-0587</orcidid><orcidid>https://orcid.org/0000-0002-3020-4966</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1522-7235 |
| ispartof | Luminescence (Chichester, England), 2024-02, Vol.39 (2), p.n/a |
| issn | 1522-7235 1522-7243 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2902973729 |
| source | Access via Wiley Online Library |
| subjects | 2‐mercaptoethanol Algorithms Benzalkonium chloride Dexamethasone Evaluation Fluorescence Multiple criterion Netilmicin o‐phthalaldehyde Reaction products Reagents Roth's reaction |
| title | Validated spectrofluorimetric method for the determination of netilmicin based on its interaction with o‐phthalaldehyde/mercaptoethanol: Evaluation of the method's greenness |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T18%3A17%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Validated%20spectrofluorimetric%20method%20for%20the%20determination%20of%20netilmicin%20based%20on%20its%20interaction%20with%20o%E2%80%90phthalaldehyde/mercaptoethanol:%20Evaluation%20of%20the%20method's%20greenness&rft.jtitle=Luminescence%20(Chichester,%20England)&rft.au=Salem%20AlSalem,%20Huda&rft.date=2024-02&rft.volume=39&rft.issue=2&rft.epage=n/a&rft.issn=1522-7235&rft.eissn=1522-7243&rft_id=info:doi/10.1002/bio.4644&rft_dat=%3Cproquest_cross%3E2902973729%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2931808667&rft_id=info:pmid/38081623&rfr_iscdi=true |