Niosomes loading N-acetyl-L-cysteine for cancer treatment in vivo study

Scientists are seeking to find an effective treatment for tumors that has no side effects. N-Acetyl-l-cysteine (NAC) is a thiol compound extracted from garlic. Current study explores the potential of NAC-loaded niosomes (NAC-NIO) for tumor treatment in mice. NAC-loaded niosomes’ efficiency, morpholo...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 2024-06, Vol.397 (6), p.4339-4353
Hauptverfasser:	Mohamad, Ebtesam A., Ali, Abeer A., Sharaky, Marwa, El-Gebaly, Reem H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine Acetylcysteine - administration & dosage Acetylcysteine - pharmacology Animals Antineoplastic Agents - administration & dosage Antineoplastic Agents - pharmacology Apoptosis - drug effects Biomedical and Life Sciences Biomedicine Cancer therapies Caspase-3 Caspase-9 Cell Line, Tumor Comet assay Cysteine DNA Damage - drug effects Drug Carriers Gene expression Liposomes Male Mice Mice, Inbred BALB C Neurosciences Nitric oxide Oral administration Oxidative stress Oxidative Stress - drug effects Pharmacology/Toxicology Size distribution Tumor Burden - drug effects Tumor cells Tumors Zeta potential
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