Butyrate ameliorated ferroptosis in ulcerative colitis through modulating Nrf2/GPX4 signal pathway and improving intestinal barrier

Oxidative stress and intestinal inflammation are main pathological features of ulcerative colitis (UC). Ferroptosis, characterized by iron accumulation and lipid peroxidation, is closely related to the pathologic process of UC. 16S rRNA sequencing for intestinal microbiota analysis and gas chromatog...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2024-02, Vol.1870 (2), p.166984-166984, Article 166984
Hauptverfasser:	Chen, Hangping, Qian, Yifan, Jiang, Chensheng, Tang, Leilei, Yu, Jiawen, Zhang, Lingdi, Dai, Yiyang, Jiang, Guojun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Butyric Acid - pharmacology Butyric Acid - therapeutic use Colitis Colitis, Ulcerative - chemically induced Colitis, Ulcerative - drug therapy Ferroptosis Iron Mice NF-E2-Related Factor 2 - genetics RNA, Ribosomal, 16S Signal Transduction
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