Mucin-mediated mucosal retention via end-terminal modified Pluronic F127-based hydrogel to increase drug accumulation in the lungs

Noninvasive lung drug delivery is critical for treating respiratory diseases. Pluronic-based copolymers have been used as multifunctional materials for medical and biological applications. However, the Pluronic F127-based hydrogel is rapidly degraded, adversely affecting the mechanical stability for...

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Veröffentlicht in:	Biomaterials advances 2024-01, Vol.156, p.213722-213722, Article 213722
Hauptverfasser:	Wu, Tsung-Yun, Huang, Chun-Chiang, Tsai, Hsieh-Chih, Lin, Tzu-Kai, Chen, Pei-Yu, Darge, Haile Fentahun, Hong, Zhen-Xiang, Harn, Horng-Jyh, Lin, Shinn-Zong, Lai, Juin-Yih, Chen, Yu-Shuan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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