Pyroptosis in glioma: Current management and future application

Summary Glioma, the predominant form of central nervous system (CNS) malignancies, presents a significant challenge due to its high prevalence and low 5‐year survival rate. The efficacy of current treatment methods is limited by the presence of the blood–brain barrier, the immunosuppressive microenv...

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Veröffentlicht in:	Immunological reviews 2024-01, Vol.321 (1), p.152-168
Hauptverfasser:	Guo, Zeshang, Su, Zhenjin, Wei, Ying, Zhang, Xingmei, Hong, Xinyu
Format:	Artikel
Sprache:	eng
Schlagworte:	antitumor Apoptosis Blood-brain barrier Brain tumors Cancer therapies Cell death Central nervous system gasdermin glioma Glioma cells Health services Immune privilege Immunotherapy Malignancy Metastases Microenvironments Pyroptosis pyroptosis‐related genes Survival targeted therapy Tumors
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