In Silico Functional and Structural Analysis of Non-synonymous Single Nucleotide Polymorphisms (nsSNPs) in Human Paired Box 4 Gene

In human genome, members of Paired box (PAX) transcription factor family are highly sequence-specific DNA-binding proteins. Among PAX gene family members, PAX4 gene has significant role in growth, proliferation, differentiation, and insulin secretion of pancreatic β-cells. Single nucleotide polymorp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical genetics 2024-08, Vol.62 (4), p.2975-2998
Hauptverfasser:	Kamal, Md. Mostafa, Islam, Md. Numan, Rabby, Md. Golam, Zahid, Md. Ashrafuzzaman, Hasan, Md. Mahmudul
Format:	Artikel
Sprache:	eng
Schlagworte:	Beta cells Biochemistry Biomedical and Life Sciences Biomedicine Cell differentiation Cell proliferation Computational Biology - methods Computer Simulation Diabetes mellitus (non-insulin dependent) DNA-binding protein Genetic Predisposition to Disease Homeodomain Proteins - genetics Human Genetics Humans Insulin secretion Medical Microbiology Molecular modelling Mutation, Missense Nucleotide sequence Nucleotides Original Article Paired Box Transcription Factors - genetics Pathogenesis Pax gene Polymorphism, Single Nucleotide Proteins Single-nucleotide polymorphism Structural analysis Structure-function relationships Zoology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!