Catalytic core function of yeast Pah1 phosphatidate phosphatase reveals structural insight into its membrane localization and activity control

The PAH1-encoded phosphatidate (PA) phosphatase is a major source of diacylglycerol for the production of the storage lipid triacylglycerol, and a key regulator for the de novo phospholipid synthesis in Saccharomyces cerevisiae. The catalytic function of Pah1 depends on its membrane localization tha...

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Veröffentlicht in:The Journal of biological chemistry 2024-01, Vol.300 (1), p.105560, Article 105560
Hauptverfasser: Han, Gil-Soo, Kwiatek, Joanna M, Hu, Kam Shan, Carman, George M
Format: Artikel
Sprache:eng
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