A case of haemolytic disease of the fetus and newborn attributed to a novel antigen in the RHAG blood group system

Background and Objectives A newborn presented with jaundice in Thailand. The cord red cells tested positive by direct antiglobulin test (DAT) for an unknown maternal red cell antibody. Initial blood group sequencing suggested that the infant carried a novel variant RHAG c.140T>C, responsible for...

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Veröffentlicht in:	Vox sanguinis 2023-12, Vol.118 (12), p.1095-1099
Hauptverfasser:	Chatterjee, Saion, Millard, Glenda, Chiawchan, Suwat, Chanthet, Sarawan, Daly, James, Hyland, Catherine, Kitpoka, Pimpin, Powley, Tanya, Liew, Yew‐Wah
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglutination Antibodies Antigens blood group Blood Group Antigens - genetics Blood groups Blood Proteins Coombs' test Erythrocytes Families & family life Fetus Fetuses Glycoproteins haemolytic disease of the fetus and newborn Hematologic Diseases Hemolysis Humans Incompatibility Infant, Newborn Infants Jaundice massive parallel sequencing Membrane Glycoproteins Nucleotides Rh-Hr Blood-Group System - genetics RHAG Rh‐associated glycoprotein Sequences serological testing Siblings
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