Treatment experience with continuous local antibiotic perfusion for periprosthetic joint infection

Antibiotic concentrations 100–1000 times higher than the minimum inhibitory concentration are necessary for eradicating biofilms in periprosthetic joint infections (PJI). Achieving this with intravenous antibiotics is challenging, but continuous local antibiotic perfusion (CLAP) can increase the loc...

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Veröffentlicht in:	Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2024-11, Vol.29 (6), p.1469-1476
Hauptverfasser:	Miyake, Yoshiaki, Takagi, Toru
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Arthroplasty, Replacement, Hip - adverse effects Arthroplasty, Replacement, Knee - adverse effects Continuous local antibiotic perfusion Debridement Debridement, antibiotics, and implant retention Female Follow-Up Studies Humans Male Middle Aged Perfusion - methods Periprosthetic joint infection Prosthesis-Related Infections - drug therapy Prosthesis-Related Infections - microbiology Reoperation Retrospective Studies Treatment Outcome
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