Autophagy Gene BECN1 Intronic Variant rs9890617 Predisposes Individuals to Hepatitis B Virus Infection

Beclin 1 protein encoded by the BECN1 gene plays a critical role in the autophagy pathway which is utilized by the Hepatitis B virus (HBV) for its replication. HBV is known for the subversion of the host’s autophagy process for its multiplication. The aim of this study was to determine the role of B...

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Veröffentlicht in:	Biochemical genetics 2024-10, Vol.62 (5), p.3336-3349
Hauptverfasser:	Kaur, Sargeet, Vashistt, Jitendraa, Changotra, Harish
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Autophagy Autophagy - genetics Beclin-1 - genetics Biochemistry Biomedical and Life Sciences Biomedicine Case-Control Studies Chronic infection Female Gene polymorphism Genetic Predisposition to Disease Genotype Health risks Hepatitis Hepatitis B Hepatitis B - genetics Hepatitis B virus Hepatitis B, Chronic - genetics Human Genetics Humans Infections Introns Male Medical Microbiology Middle Aged Mutants Original Article Polymerase chain reaction Polymorphism Polymorphism, Single Nucleotide Restriction fragment length polymorphism Statistical analysis Statistical models Zoology
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