Changes in neuroinflammatory markers and microglial density in the hippocampus and prefrontal cortex of the C58/J mouse model of autism

Autism spectrum disorder (ASD) is a diverse group of neurodevelopmental conditions with complex origins. Individuals with ASD present various neurobiological abnormalities, including an altered immune response in the central nervous system and other tissues. Animal models like the C58/J inbred mouse...

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Veröffentlicht in:	The European journal of neuroscience 2024-01, Vol.59 (1), p.154-173
Hauptverfasser:	Duarte‐Campos, Juan F., Vázquez‐Moreno, C. Noé, Martínez‐Marcial, Mónica, Chavarría, Anahí, Ramírez‐Carreto, Ricardo Jair, Velasco Velázquez, Marco A., De La Fuente‐Granada, Marisol, González‐Arenas, Aliesha
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Arginase Autism autism spectrum disorder Autism Spectrum Disorder - metabolism Autistic Disorder - metabolism Central nervous system CX3CR1 protein Dendritic spines Disease Models, Animal Fractalkine Hippocampus Hippocampus - metabolism Immune response Inbreeding Inflammation Inflammation - metabolism Interferon Male Mice Mice, Inbred C57BL Mice, Inbred Strains microglia Microglia - metabolism Monocyte chemoattractant protein Monocyte chemoattractant protein 1 Monocytes neuroinflammation Prefrontal cortex Prefrontal Cortex - metabolism proinflammatory cytokines Social behavior
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