Polymerizable 2‑Propionic-3-methylmaleic Anhydrides as a Macromolecular Carrier Platform for pH-Responsive Immunodrug Delivery

The design of functional polymers coupled with stimuli-triggered drug release mechanisms is a promising achievement to overcome various biological barriers. pH trigger methods yield significant potential for controlled targeting and release of therapeutics due to their simplicity and relevance, espe...

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Veröffentlicht in:	Journal of the American Chemical Society 2023-12, Vol.145 (50), p.27424-27436
Hauptverfasser:	Heck, Alina G., Stickdorn, Judith, Rosenberger, Laura J., Scherger, Maximilian, Woller, Jonas, Eigen, Katharina, Bros, Matthias, Grabbe, Stephan, Nuhn, Lutz
Format:	Artikel
Sprache:	eng
Schlagworte:	acidification Amines - chemistry Anhydrides Citraconic Anhydrides dimethyl sulfoxide drugs Hydrogen-Ion Concentration hydrophilicity immunotherapy polymerization polymers Polymers - chemistry toxicity
Online-Zugang:	Volltext
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