Stimulus-Induced Relief of Intentionally Incorporated Frustration Drives Refolding of a Water-Soluble Biomimetic Foldamer

Frustrated, or nonoptimal, interactions have been proposed to be essential to a protein’s ability to display responsive behavior such as allostery, conformational signaling, and signal transduction. However, the intentional incorporation of frustrated noncovalent interactions has not been explored a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the American Chemical Society 2023-12, Vol.145 (50), p.27672-27679
Hauptverfasser: Henriksen, Hanne C., Sowers, Adam J., Travis, Christopher R., Vulpis, Troy D., Cope, Thomas A., Ouslander, Sarah K., Russell, Alexander F., Gagné, Michel R., Pophristic, Vojislava, Liu, Zhiwei, Waters, Marcey L.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!