Stimulus-Induced Relief of Intentionally Incorporated Frustration Drives Refolding of a Water-Soluble Biomimetic Foldamer
Frustrated, or nonoptimal, interactions have been proposed to be essential to a protein’s ability to display responsive behavior such as allostery, conformational signaling, and signal transduction. However, the intentional incorporation of frustrated noncovalent interactions has not been explored a...
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Veröffentlicht in: | Journal of the American Chemical Society 2023-12, Vol.145 (50), p.27672-27679 |
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