Upregulated Tβ4 expression in inflammatory bowel disease impairs the intestinal mucus barrier by inhibiting autophagy in mice

Disrupted intestinal barrier homeostasis is fundamental to inflammatory bowel disease. Thymosin β4 (Tβ4) improves inflammation and has beneficial effects in dry-eye diseases, but its effects on the intestinal mucus barrier remain unknown. Therefore, this study evaluated the underlying regulatory mec...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental cell research 2024-01, Vol.434 (1), p.113871-113871, Article 113871
Hauptverfasser: Hao, Menghao, Zhong, Ke, Bai, Xiaoqin, Wu, Shiyan, Li, Lu, He, Yumei, Wang, Zhiming, Sun, Xiaobin, Wang, Qiong, Guo, Yuanbiao, Sun, Yueshan, Wu, Liping
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!