Time-Dependent Differences in Vancomycin Sensitivity of Macrophages Underlie Vancomycin-Induced Acute Kidney Injury

Although vancomycin (VCM)—frequently used to treat drug-resistant bacterial infections—often induces acute kidney injury (AKI), discontinuation of the drug is the only effective treatment; therefore, analysis of effective avoidance methods is urgently needed. Here, we report the differences in the i...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2024-01, Vol.388 (1), p.218-227
Hauptverfasser:	Yoshida, Yuya, Fukuda, Taiki, Fukuoka, Kohei, Nagayama, Toshitaka, Tanihara, Tomohito, Nishikawa, Naoki, Otsuki, Kaita, Terada, Yuma, Hamamura, Kengo, Oyama, Kosuke, Tsuruta, Akito, Mayanagi, Kota, Koyanagi, Satoru, Matsunaga, Naoya, Ohdo, Shigehiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - chemically induced Acute Kidney Injury - metabolism Animals Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology Kidney Macrophages Mice Vancomycin - metabolism Vancomycin - pharmacology
Online-Zugang:	Volltext
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