Histopathologic regression in patients with primary cutaneous melanoma undergoing sentinel lymph node biopsy is associated with favorable survival and, after metastasis, with improved progression-free survival on immune checkpoint inhibitor therapy: A single-institutional cohort study

Histopathologic regression of cutaneous melanoma is considered a favorable prognostic factor, but its significance in clinical practice remains controversial. To investigate the prognostic importance of regression in patients with primary cutaneous melanoma undergoing sentinel lymph node (SLN) biops...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 2024-04, Vol.90 (4), p.739-748
Hauptverfasser:	Wagner, Nikolaus B., Knierim, Sarah M., Luttermann, Felix, Metzler, Gisela, Yazdi, Amir S., Bauer, Jürgen, Gassenmaier, Maximilian, Forschner, Andrea, Leiter, Ulrike, Amaral, Teresa, Garbe, Claus, Eigentler, Thomas K., Forchhammer, Stephan, Flatz, Lukas
Format:	Artikel
Sprache:	eng
Schlagworte:	chemotherapy clinical research Cohort Studies cutaneous melanoma drug response histopathologic regression Humans immune checkpoint inhibition Immune Checkpoint Inhibitors Melanoma - pathology Neoplasm Recurrence, Local - pathology oncology Prognosis Progression-Free Survival Retrospective Studies Sentinel Lymph Node - pathology Sentinel Lymph Node Biopsy Skin Neoplasms - pathology targeted therapy
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