A case of pulmonary edema due to guanfacine intoxication with measurement of serum guanfacine concentrations

Guanfacine hydrochloride extended-release (GXR) is used to treat attention deficit hyperactivity disorder. It is a selective α2A-adrenorecepor agonist that was reported to cause QT prolongation and hypotension in the event of overdosing. We report the case of a 17-year-old man who took 226 tablets o...

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Veröffentlicht in:	Journal of toxicological sciences 2023, Vol.48(12), pp.641-644
Hauptverfasser:	Ayata, Ryo, Fujita, Motoki, Harada, Kayoko, Esaki, Yusuke, Koga, Yasutaka, Hisamoto, Yukari, Asami-Noyama, Maki, Takeda, Saki, Harada, Kazuki, Tsuruta, Ryosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenergic alpha-2 Receptor Agonists - adverse effects Attention Deficit Disorder with Hyperactivity - drug therapy Delayed-Action Preparations - adverse effects Guanfacine Guanfacine - blood Guanfacine - toxicity Heart failure Humans Intoxication Male Pulmonary edema Pulmonary Edema - chemically induced Serum concentration
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