Role of Rho Kinase in Regulating Arterial Stiffness in Anesthetized Rabbits

The effects of Rho kinase inhibitors fasudil and ripasudil on arterial stiffness were assessed using anesthetized rabbits, where the aortic β and femoral β were measured as a stiffness parameter at each arterial region. Intravenous administration of fasudil and ripasudil dose-dependently decreased b...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2023/12/01, Vol.46(12), pp.1846-1850
Hauptverfasser:	Takahara, Akira, Matsumoto, Manami, Sato, Akira, Inose, Shuto, Aimoto, Megumi, Nagasawa, Yoshinobu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aorta arterial stiffness Blood flow Blood pressure Femoral artery Femur Intravenous administration Muscle contraction Rho kinase inhibitor Rho-associated kinase Smooth muscle
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