Cytomegalovirus Infection Facilitates the Costimulation of CD57+CD28- CD8 T Cells in HIV Infection and Atherosclerosis via the CD2-LFA-3 Axis

CD8 T cells are emerging as important mediators in atherosclerosis and cardiovascular disease (CVD). Immune activation may play a particular role in people with HIV (PWH) who are at an increased risk of CVD, even after controlling for known CVD risk factors. Latent CMV infection is associated with i...

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Veröffentlicht in:	The Journal of immunology (1950) 2024-01, Vol.212 (2), p.245-257
Hauptverfasser:	Winchester, Nicole E, Panigrahi, Soumya, Haria, Anokhi, Chakraborty, Archeesha, Su, Xi, Chen, Bonnie, Morris, Stephen R, Clagett, Brian M, Juchnowski, Steven M, Yadavalli, Raghavendra, Villinger, Francois, Paiardini, Mirko, Harth, Karem, Kashyap, Vikram S, Calabrese, Leonard H, Margolis, Leonid, Sieg, Scott F, Shive, Carey L, Gianella, Sara, Funderburg, Nicholas T, Zidar, David A, Lederman, Michael M, Freeman, Michael L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis - metabolism Cardiovascular Diseases CD28 Antigens - metabolism CD4-Positive T-Lymphocytes CD58 Antigens - metabolism CD8-Positive T-Lymphocytes Cytomegalovirus Cytomegalovirus Infections HIV Infections - drug therapy Humans Macaca mulatta
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