SCD1 is the critical signaling hub to mediate metabolic diseases: Mechanism and the development of its inhibitors

Metabolic diseases, featured with dysregulated energy homeostasis, have become major global health challenges. Patients with metabolic diseases have high probability to manifest multiple complications in lipid metabolism, e.g. obesity, insulin resistance and fatty liver. Therefore, targeting the hub...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2024-01, Vol.170, p.115586-115586, Article 115586
Hauptverfasser:	Sun, Qin, Xing, Xiaorui, Wang, Huanyu, Wan, Kang, Fan, Ruobing, Liu, Cheng, Wang, Yongjian, Wu, Wenyi, Wang, Yibing, Wang, Ru
Format:	Artikel
Sprache:	eng
Schlagworte:	Fatty Acids - metabolism Fatty Acids, Monounsaturated Fatty Liver Humans Inflammation Insulin Resistance Metabolic diseases Metabolic homeostasis Monounsaturated fatty acids Obesity - drug therapy Obesity - metabolism Saturated fatty acids Stearoyl-CoA Desaturase - genetics Stearoyl-CoA Desaturase - metabolism Stearoyl-CoA desaturase 1
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