Crosstalk between GABAA receptors in astrocytes and neurons triggered by general anesthetic drugs

General anesthetic drugs cause cognitive deficits that persist after the drugs have been eliminated. Astrocytes may contribute to such cognition-impairing effects through the release of one or more paracrine factors that increase a tonic inhibitory conductance generated by extrasynaptic γ-aminobutyr...

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Veröffentlicht in:Translational research : the journal of laboratory and clinical medicine 2024-05, Vol.267, p.39-53
Hauptverfasser: Wang, Dian-Shi, Ju, Li, Pinguelo, Arsène G., Kaneshwaran, Kirusanthy, Haffey, Sean C., Lecker, Irene, Gohil, Himaben, Wheeler, Michael B., Kaustov, Lilia, Ariza, Anthony, Yu, MeiFeng, Volchuk, Allen, Steinberg, Benjamin E., Goldenberg, Neil M., Orser, Beverley A.
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Sprache:eng
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