Genomic alterations driving precancerous to cancerous lesions in esophageal cancer development

Esophageal squamous cell carcinoma (ESCC) develops through a series of increasingly abnormal precancerous lesions. Previous studies have revealed the striking differences between normal esophageal epithelium and ESCC in copy number alterations (CNAs) and mutations in genes driving clonal expansion....

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Veröffentlicht in:	Cancer cell 2023-12, Vol.41 (12), p.2038-2050.e5
Hauptverfasser:	Chang, Jiang, Zhao, Xuan, Wang, Yichen, Liu, Tianyuan, Zhong, Ce, Lao, Yueqiong, Zhang, Shaosen, Liao, Han, Bai, Fan, Lin, Dongxin, Wu, Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Esophageal Neoplasms - genetics Esophageal Neoplasms - pathology Esophageal Squamous Cell Carcinoma - genetics Genomics Humans Precancerous Conditions - genetics Precancerous Conditions - pathology
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