A novel program of infiltrative control in astrocytomas: ADAM23 depletion promotes cell invasion by activating γ-secretase complex

Abstract Background Infiltration is a life-threatening growth pattern in malignant astrocytomas and a significant cause of therapy resistance. It results in the tumor cell spreading deeply into the surrounding brain tissue, fostering tumor recurrence and making complete surgical resection impossible...

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Veröffentlicht in:	Neuro-oncology advances 2023-01, Vol.5 (1), p.vdad147-vdad147
Hauptverfasser:	Jandrey, Elisa Helena Farias, Barnabé, Gabriela Filoso, Maldaun, Marcos, Asprino, Paula Fontes, dos Santos, Natália Cristina, Inoue, Lilian Tiemi, Rozanski, Andrei, Galante, Pedro Alexandre Favoretto, Marie, Suely Kazue Nagahashi, Oba-Shinjo, Sueli Mieko, dos Santos, Tiago Góss, Chammas, Roger, Lancellotti, Carmen Lucia Penteado, Furnari, Frank B, Camargo, Anamaria Aranha, Costa, Érico Tosoni
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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