Rise of synthetic yeast: Charting courses to new applications
Microbes have long provided us with important capabilities, and the genome engineering of microbes has greatly empowered research and applications in biotechnology. This is especially true with the emergence of synthetic biology and recent advances in genome engineering to control microbial behavior...
Gespeichert in:
| Veröffentlicht in: | Cell genomics 2023-11, Vol.3 (11), p.100438, Article 100438 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 11 |
| container_start_page | 100438 |
| container_title | Cell genomics |
| container_volume | 3 |
| creator | Taghon, Geoffrey J Strychalski, Elizabeth A |
| description | Microbes have long provided us with important capabilities, and the genome engineering of microbes has greatly empowered research and applications in biotechnology. This is especially true with the emergence of synthetic biology and recent advances in genome engineering to control microbial behavior. A fully synthetic, rationally designed genome promises opportunities for unprecedented control of cellular function. As a eukaryotic workhorse for research and industrial use, yeast is an organism at the forefront of synthetic biology; the tools and engineered cellular platform being delivered by the Sc2.0 consortium are enabling a new era of bespoke biology. This issue highlights recent advances delivered by this consortium, but hurdles remain to maximize the impact of engineered eukaryotic cells more broadly. |
| doi_str_mv | 10.1016/j.xgen.2023.100438 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2895703592</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2895703592</sourcerecordid><originalsourceid>FETCH-LOGICAL-c347t-944d9503ea88f5ece566280fe63a7dfbb898222b5a46818f2a19a2efb2c8acfe3</originalsourceid><addsrcrecordid>eNpNkF1LwzAUhoMoTub-gBeSS28605M2TQQvZPgFA0EUvAtpdrJldG1tUnT_3o5N8eq8HJ73vXgIuUjZNGWpuF5Pv5dYT4EBHx4s4_KInIEQIlGF-jj-l0dkEsKaMQZyAAt-SkZcMmBKiDNy--oD0sbRsK3jCqO3dIsmxBs6W5ku-npJbdN3AQONDa3xi5q2rbw10Td1OCcnzlQBJ4c7Ju8P92-zp2T-8vg8u5snlmdFTFSWLVTOOBopXY4WcyFAMoeCm2LhylIqCQBlbjIhU-nApMoAuhKsNNYhH5Or_W7bNZ89hqg3PlisKlNj0wcNUuUF47mCAYU9arsmhA6dbju_Md1Wp0zvzOm13pnTO3N6b24oXR72-3KDi7_Kryf-A5M7auw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2895703592</pqid></control><display><type>article</type><title>Rise of synthetic yeast: Charting courses to new applications</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Taghon, Geoffrey J ; Strychalski, Elizabeth A</creator><creatorcontrib>Taghon, Geoffrey J ; Strychalski, Elizabeth A</creatorcontrib><description>Microbes have long provided us with important capabilities, and the genome engineering of microbes has greatly empowered research and applications in biotechnology. This is especially true with the emergence of synthetic biology and recent advances in genome engineering to control microbial behavior. A fully synthetic, rationally designed genome promises opportunities for unprecedented control of cellular function. As a eukaryotic workhorse for research and industrial use, yeast is an organism at the forefront of synthetic biology; the tools and engineered cellular platform being delivered by the Sc2.0 consortium are enabling a new era of bespoke biology. This issue highlights recent advances delivered by this consortium, but hurdles remain to maximize the impact of engineered eukaryotic cells more broadly.</description><identifier>ISSN: 2666-979X</identifier><identifier>EISSN: 2666-979X</identifier><identifier>DOI: 10.1016/j.xgen.2023.100438</identifier><identifier>PMID: 38020966</identifier><language>eng</language><publisher>United States</publisher><ispartof>Cell genomics, 2023-11, Vol.3 (11), p.100438, Article 100438</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-944d9503ea88f5ece566280fe63a7dfbb898222b5a46818f2a19a2efb2c8acfe3</citedby><cites>FETCH-LOGICAL-c347t-944d9503ea88f5ece566280fe63a7dfbb898222b5a46818f2a19a2efb2c8acfe3</cites><orcidid>0000-0003-0438-0509 ; 0000-0002-5350-5075</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,862,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38020966$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Taghon, Geoffrey J</creatorcontrib><creatorcontrib>Strychalski, Elizabeth A</creatorcontrib><title>Rise of synthetic yeast: Charting courses to new applications</title><title>Cell genomics</title><addtitle>Cell Genom</addtitle><description>Microbes have long provided us with important capabilities, and the genome engineering of microbes has greatly empowered research and applications in biotechnology. This is especially true with the emergence of synthetic biology and recent advances in genome engineering to control microbial behavior. A fully synthetic, rationally designed genome promises opportunities for unprecedented control of cellular function. As a eukaryotic workhorse for research and industrial use, yeast is an organism at the forefront of synthetic biology; the tools and engineered cellular platform being delivered by the Sc2.0 consortium are enabling a new era of bespoke biology. This issue highlights recent advances delivered by this consortium, but hurdles remain to maximize the impact of engineered eukaryotic cells more broadly.</description><issn>2666-979X</issn><issn>2666-979X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNpNkF1LwzAUhoMoTub-gBeSS28605M2TQQvZPgFA0EUvAtpdrJldG1tUnT_3o5N8eq8HJ73vXgIuUjZNGWpuF5Pv5dYT4EBHx4s4_KInIEQIlGF-jj-l0dkEsKaMQZyAAt-SkZcMmBKiDNy--oD0sbRsK3jCqO3dIsmxBs6W5ku-npJbdN3AQONDa3xi5q2rbw10Td1OCcnzlQBJ4c7Ju8P92-zp2T-8vg8u5snlmdFTFSWLVTOOBopXY4WcyFAMoeCm2LhylIqCQBlbjIhU-nApMoAuhKsNNYhH5Or_W7bNZ89hqg3PlisKlNj0wcNUuUF47mCAYU9arsmhA6dbju_Md1Wp0zvzOm13pnTO3N6b24oXR72-3KDi7_Kryf-A5M7auw</recordid><startdate>20231108</startdate><enddate>20231108</enddate><creator>Taghon, Geoffrey J</creator><creator>Strychalski, Elizabeth A</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0438-0509</orcidid><orcidid>https://orcid.org/0000-0002-5350-5075</orcidid></search><sort><creationdate>20231108</creationdate><title>Rise of synthetic yeast: Charting courses to new applications</title><author>Taghon, Geoffrey J ; Strychalski, Elizabeth A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-944d9503ea88f5ece566280fe63a7dfbb898222b5a46818f2a19a2efb2c8acfe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Taghon, Geoffrey J</creatorcontrib><creatorcontrib>Strychalski, Elizabeth A</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cell genomics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Taghon, Geoffrey J</au><au>Strychalski, Elizabeth A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rise of synthetic yeast: Charting courses to new applications</atitle><jtitle>Cell genomics</jtitle><addtitle>Cell Genom</addtitle><date>2023-11-08</date><risdate>2023</risdate><volume>3</volume><issue>11</issue><spage>100438</spage><pages>100438-</pages><artnum>100438</artnum><issn>2666-979X</issn><eissn>2666-979X</eissn><abstract>Microbes have long provided us with important capabilities, and the genome engineering of microbes has greatly empowered research and applications in biotechnology. This is especially true with the emergence of synthetic biology and recent advances in genome engineering to control microbial behavior. A fully synthetic, rationally designed genome promises opportunities for unprecedented control of cellular function. As a eukaryotic workhorse for research and industrial use, yeast is an organism at the forefront of synthetic biology; the tools and engineered cellular platform being delivered by the Sc2.0 consortium are enabling a new era of bespoke biology. This issue highlights recent advances delivered by this consortium, but hurdles remain to maximize the impact of engineered eukaryotic cells more broadly.</abstract><cop>United States</cop><pmid>38020966</pmid><doi>10.1016/j.xgen.2023.100438</doi><orcidid>https://orcid.org/0000-0003-0438-0509</orcidid><orcidid>https://orcid.org/0000-0002-5350-5075</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2666-979X |
| ispartof | Cell genomics, 2023-11, Vol.3 (11), p.100438, Article 100438 |
| issn | 2666-979X 2666-979X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2895703592 |
| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| title | Rise of synthetic yeast: Charting courses to new applications |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T20%3A46%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Rise%20of%20synthetic%20yeast:%20Charting%20courses%20to%20new%20applications&rft.jtitle=Cell%20genomics&rft.au=Taghon,%20Geoffrey%20J&rft.date=2023-11-08&rft.volume=3&rft.issue=11&rft.spage=100438&rft.pages=100438-&rft.artnum=100438&rft.issn=2666-979X&rft.eissn=2666-979X&rft_id=info:doi/10.1016/j.xgen.2023.100438&rft_dat=%3Cproquest_cross%3E2895703592%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2895703592&rft_id=info:pmid/38020966&rfr_iscdi=true |