Driver gene KRAS aggravates cancer-associated stroke outcomes

The incidence of cancer-associated stroke has increased with the prolonged survival times of cancer patients. Recent genetic studies have led to progress in cancer therapeutics, but relationships between oncogenic mutations and stroke remain elusive. Here, we focused on the driver gene KRAS, which i...

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Veröffentlicht in:	Thrombosis research 2024-01, Vol.233, p.55-68
Hauptverfasser:	Yan, Haomin, Sasaki, Tsutomu, Gon, Yasufumi, Nishiyama, Kumiko, Kanki, Hideaki, Mochizuki, Hideki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Colorectal Neoplasms - complications Colorectal Neoplasms - genetics HCT116 Cells - metabolism Humans Ischemic Stroke Mice Mutation Proto-Oncogene Proteins p21(ras) - genetics Stroke - complications Stroke - genetics
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