Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis

Purpose The blood-brain barrier can prevent circulating tumor DNA (ctDNA) derived from the central nervous system from entering the blood making it challenging to evaluate molecular features of leptomeningeal metastasis (LM). Accordingly, we sought to systematically compare the diagnostic power or s...

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Veröffentlicht in:	Journal of neuro-oncology 2023-12, Vol.165 (3), p.431-438
Hauptverfasser:	Wijaya, Jeremiah H., Patel, Utsav D., Quintero-Consuegra, Miguel D., Aguilera-Peña, Maria P., Madriñán-Navia, Humberto J., Putra, Aulia W., July, Julius, Kataria, Saurabh
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - analysis Biopsy Blood-brain barrier Brain tumors Central nervous system Central Nervous System - chemistry Central Nervous System - pathology Cerebrospinal fluid Circulating Tumor DNA - cerebrospinal fluid Circulating Tumor DNA - genetics Humans Liquid Biopsy Medicine Medicine & Public Health Meningeal Carcinomatosis - diagnosis Meninges Meta-analysis Metastases Metastasis Mutation Neoplastic Cells, Circulating - pathology Neurology Oncology Review Systematic review
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