Adding a Gene Expression Profile Test to Aid Differential Diagnosis and Treatment in Aggressive Large B-Cell Lymphoma: An Early Exploratory Economic Evaluation

Background and Objective Adding gene expression profiles (GEPs) to the current diagnostic work-up of aggressive large B-cell lymphomas may lead to the reclassification of patients, treatment changes and improved outcomes. A GEP test is in development using TempO-Seq ® technology to distinguish Burki...

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Veröffentlicht in:	Applied health economics and health policy 2024-03, Vol.22 (2), p.243-254
Hauptverfasser:	Bouttell, Janet, Fraser, Heather, Goodlad, John R., Hopkins, David, McKay, Pam, Oien, Karin A., Seligmann, Bruce, von Delft, Stephan, Hawkins, Neil
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood cancer Bortezomib - therapeutic use Clinical trials Cost analysis Cost-Benefit Analysis Costs Cyclophosphamide - therapeutic use Decision analysis Decision trees Diagnosis, Differential Doxorubicin - therapeutic use Estimates Gene expression Genetic testing Health Administration Health care expenditures Health Economics Hematology Humans Lymphoma Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - drug therapy Lymphoma, Large B-Cell, Diffuse - genetics Medical diagnosis Medical treatment Medicine Medicine & Public Health Original Research Article Patients Pharmacoeconomics and Health Outcomes Prices Probability Public Health Quality of Life Research Quality-Adjusted Life Years Return on investment Rituximab - therapeutic use Sensitivity analysis Transcriptome
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