Molecular PET/CT mapping of rhACE2 distribution and quantification in organs to aid in SARS‐CoV‐2 targeted therapy

Coronavirus disease 2019 (COVID‐19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, poses a significant threat to public health. Angiotensin‐converting enzyme 2 (ACE2) is a key receptor for SARS‐CoV‐2 infection. Recombinant human ACE2 (RhACE2), as a solubl...

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Veröffentlicht in:	Journal of medical virology 2023-11, Vol.95 (11), p.e29221-n/a
Hauptverfasser:	Wang, Zilei, Zhao, Chuanke, Li, Chuangui, Liu, Song, Ding, Jin, He, Chengxue, Liu, Jiayue, Dong, Bin, Yang, Zhi, Liu, Qi, Zhu, Hua, Liu, Youping
Format:	Artikel
Sprache:	eng
Schlagworte:	68Ga‐HZ20 ACE2 Angiotensin Angiotensin-Converting Enzyme 2 Animals Circulatory system Coronaviruses COVID-19 COVID-19 - diagnostic imaging Disease Models, Animal Health risks Humans Infections Kidneys Medical imaging Mice Organs Peptidyl-Dipeptidase A PET imaging Positron emission Positron emission tomography Positron Emission Tomography Computed Tomography Public health Radioactive tracers Radiochemistry Respiratory diseases rhACE2‐organ model SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Viral diseases Virology
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