GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion

PurposeThis study aimed to explore the impact of GSK840 on retinal neuronal injury after retinal ischemia/reperfusion (IR) and its associated mechanism.MethodsWe established an in vivo mouse model of IR and an in vitro model of oxygen and glucose deprivation/reoxygenation (OGDR) in primary mouse ret...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2023-11, Vol.64 (14), p.42-42
Hauptverfasser:	Feng, Yanlin, Hu, Chenyang, Cui, Kaixuan, Fan, Matthew, Xiang, Wu, Ye, Dan, Shi, Yuxun, Ye, Huiwen, Bai, Xue, Wei, Yantao, Xu, Yue, Huang, Jingjing
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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