The protective effect of aqueous extract of Stevia rebaudiana against tartrazine toxicity in male Wistar rat

Tartrazine is a yellow colouring agent that is commonly used in foods; however, high dosages of Tartrazine affect fertility and create oxidative stress by generating free radicals. A plant species known as Stevia rebaudiana has natural antioxidants that show promise for protecting testicular tissue....

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Veröffentlicht in:	Cell biochemistry and function 2023-12, Vol.41 (8), p.1462-1476
Hauptverfasser:	Hanna, Demiana H., Beshay, Sylvia Nabil, El. Shafee, E., El‐Rahman, Heba Ali Abd
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Animals antioxidant enzymes Antioxidants Antioxidants - metabolism Antioxidants - pharmacology Catalase Coloring agents Crem gene Cyclic AMP Cyclic AMP response element modulator Damage Deoxyribonucleic acid Distilled water DNA DNA damage Empirical analysis Fertility Free radicals Gas chromatography Gene expression Glutathione Glutathione reductase Herbal medicine Immunoassays Infertility Kidneys Liver Male Males Mass spectrometry Mass spectroscopy Medical treatment Oxidative Stress Parameters Pharmacology Plant Extracts - chemistry Plant Extracts - pharmacology Plant species Polymerase chain reaction Proteins Rats Rats, Wistar Reductases Regulatory sequences Seeds - metabolism Side effects Sperm Sperm Motility Stevia Stevia - chemistry Stevia - metabolism Stevia rebaudiana Superoxide Dismutase - metabolism Tartrazine Tartrazine - metabolism Tartrazine - toxicity Testes Testis Testosterone Testosterone - pharmacology Toxicity Water - metabolism Water - pharmacology
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