(5R)-5-hydroxytriptolide ameliorates diabetic kidney damage by inhibiting macrophage infiltration and its cross-talk with renal resident cells

Diabetic nephropathy (DN) is the main cause of end-stage renal disease, and there are no targeted treatment options at present. The efficacy of the new immunosuppressive drug (5R)-5-hydroxytriptolide (LLDT8) in improving kidney inflammation has been demonstrated in multiple studies. The present stud...

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Veröffentlicht in:International immunopharmacology 2024-01, Vol.126, p.111253-111253, Article 111253
Hauptverfasser: Jianbin, Xu, Peng, Du, Jing, Zhao, Xiaofei, An, Yudie, Fang, Jing, Zhang, Yanping, Yang, Xiaorong, Yang, Kaida, Mu, Jinan, Zhang
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Sprache:eng
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