LRP5 competes for SPOP binding to enhance tumorigenesis mediated by Daxx and PD-L1 in prostate cancer

Genetic factors coordinate with environmental factors to drive the pathogenesis of prostate adenocarcinoma (PRAD). SPOP is one of the most mutated genes and LRP5 mediates lipid metabolism that is abnormally altered in PRAD. Here, we investigated the potential cross-talk between SPOP and LRP5 in PRAD...

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Veröffentlicht in:	Experimental cell research 2024-01, Vol.434 (1), p.113857-113857, Article 113857
Hauptverfasser:	Gan, Sishun, Qu, Fajun, Zhang, Xiangmin, Pan, Xiuwu, Xu, Da, Cui, Xingang, Hou, Jianquan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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