Indoleamine 2, 3-dioxygenase-transfected bone marrow-derived mesenchymal stem cells promote corneal allograft survival by inhibiting T cell proliferation: A rat study

Allograft rejection is still the main cause of corneal transplantation failure. Therefore, we investigated the role of indoleamine 2,3-dioxygenase (IDO)-transfected bone marrow-derived mesenchymal stem cells (IDO-BMSCs) in corneal allograft rejection in rats. IDO-BMSCs were constructed and co-cultur...

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Veröffentlicht in:	Transplant immunology 2024-02, Vol.82, p.101960-101960, Article 101960
Hauptverfasser:	Ke, Hongqin, Zhang, Wenjia, Xu, Wenrong, Cao, Qian, Li, Lan, Liu, Hai
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow - metabolism CD8-Positive T-Lymphocytes Cell Proliferation Corneal Transplantation Graft Rejection Graft Survival Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism Mesenchymal Stem Cells Rats
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