Working Mechanisms of Exposure and Response Prevention in the Treatment of Tourette Syndrome and Tic Disorders Revisited: No Evidence for within-Session Habituation to Premonitory Urges
Exposure and response prevention (ERP) has been shown to be an effective treatment for Tourette syndrome (TS) and chronic tic disorders (CTD). ERP is based on voluntary tic suppression in combination with prolonged exposure to premonitory urges preceding tics. A prevailing hypothesis of the working...
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| Veröffentlicht in: | Journal of clinical medicine 2023-11, Vol.12 (22), p.7087 |
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| container_title | Journal of clinical medicine |
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| creator | van de Griendt, Jolande M T M van den Berg, Nelleke M E Verdellen, Cara W J Cath, Daniëlle C Verbraak, Marc J P M |
| description | Exposure and response prevention (ERP) has been shown to be an effective treatment for Tourette syndrome (TS) and chronic tic disorders (CTD). ERP is based on voluntary tic suppression in combination with prolonged exposure to premonitory urges preceding tics. A prevailing hypothesis of the working mechanism underlying ERP in tics is habituation to the premonitory urges as a result of prolonged exposure. However, results so far are equivocal. This study aims to further explore the relation between urges and ERP in tics, by investigating the course of premonitory urges during ERP sessions.
Using a data-driven approach, within-session habituation to premonitory urge intensity was investigated. In total, 29 TS patients rated urge intensity at seven timepoints during ten 1 h ERP sessions.
Latent growth modeling showed an increase in urge intensity during the first 15 min of each session followed by a plateau in the remaining 45 min of the session. This does not support the idea of within-session habituation to premonitory urges as a working mechanism of ERP. Other potential underlying working mechanisms are discussed and should be tested in future research. |
| doi_str_mv | 10.3390/jcm12227087 |
| format | Article |
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Using a data-driven approach, within-session habituation to premonitory urge intensity was investigated. In total, 29 TS patients rated urge intensity at seven timepoints during ten 1 h ERP sessions.
Latent growth modeling showed an increase in urge intensity during the first 15 min of each session followed by a plateau in the remaining 45 min of the session. This does not support the idea of within-session habituation to premonitory urges as a working mechanism of ERP. Other potential underlying working mechanisms are discussed and should be tested in future research.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm12227087</identifier><identifier>PMID: 38002700</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Age ; Anxiety ; Behavior modification ; Care and treatment ; Clinical medicine ; Enterprise resource planning ; Hypotheses ; Patients ; Prevention ; Tourette syndrome ; Tourette's syndrome</subject><ispartof>Journal of clinical medicine, 2023-11, Vol.12 (22), p.7087</ispartof><rights>COPYRIGHT 2023 MDPI AG</rights><rights>2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-827ec28663e0b5d50374a8255b3a6a61f84a330e37e1e90198d7434b2130a7b33</citedby><cites>FETCH-LOGICAL-c421t-827ec28663e0b5d50374a8255b3a6a61f84a330e37e1e90198d7434b2130a7b33</cites><orcidid>0000-0001-9653-0935</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38002700$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van de Griendt, Jolande M T M</creatorcontrib><creatorcontrib>van den Berg, Nelleke M E</creatorcontrib><creatorcontrib>Verdellen, Cara W J</creatorcontrib><creatorcontrib>Cath, Daniëlle C</creatorcontrib><creatorcontrib>Verbraak, Marc J P M</creatorcontrib><title>Working Mechanisms of Exposure and Response Prevention in the Treatment of Tourette Syndrome and Tic Disorders Revisited: No Evidence for within-Session Habituation to Premonitory Urges</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>Exposure and response prevention (ERP) has been shown to be an effective treatment for Tourette syndrome (TS) and chronic tic disorders (CTD). ERP is based on voluntary tic suppression in combination with prolonged exposure to premonitory urges preceding tics. A prevailing hypothesis of the working mechanism underlying ERP in tics is habituation to the premonitory urges as a result of prolonged exposure. However, results so far are equivocal. This study aims to further explore the relation between urges and ERP in tics, by investigating the course of premonitory urges during ERP sessions.
Using a data-driven approach, within-session habituation to premonitory urge intensity was investigated. In total, 29 TS patients rated urge intensity at seven timepoints during ten 1 h ERP sessions.
Latent growth modeling showed an increase in urge intensity during the first 15 min of each session followed by a plateau in the remaining 45 min of the session. This does not support the idea of within-session habituation to premonitory urges as a working mechanism of ERP. Other potential underlying working mechanisms are discussed and should be tested in future research.</description><subject>Age</subject><subject>Anxiety</subject><subject>Behavior modification</subject><subject>Care and treatment</subject><subject>Clinical medicine</subject><subject>Enterprise resource planning</subject><subject>Hypotheses</subject><subject>Patients</subject><subject>Prevention</subject><subject>Tourette syndrome</subject><subject>Tourette's syndrome</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkk1v1DAQhiMEolXpiTuyxAUJpfgjiR1uVVkoUvkQ3Ypj5DiTXS8be_E42-5P49_hdAsUhH2wNXreecfjybKnjJ4IUdNXKzMwzrmkSj7IDjmVMqdCiYf37gfZMeKKpqVUwZl8nB0IRWnS0MPsx1cfvlm3IB_ALLWzOCDxPZndbDyOAYh2HfkCuPEOgXwOsAUXrXfEOhKXQOYBdBxSbBLNfVLECORy57rgh716bg15Y9GHDgKmXFuLNkL3mnz0ZLa1HTgDpPeBXNu4tC6_BMTJ4Vy3No761i36yXvwzkYfduQqLACfZI96vUY4vjuPsqu3s_nZeX7x6d37s9OL3KTHxlxxCYarqhJA27IrqZCFVrwsW6ErXbFeFVoICkICg5qyWnWyEEXLmaBatkIcZS_2eTfBfx8BYzNYNLBeawd-xIarOjW5TJ-R0Of_oKvUEpequ6VopSpW_aEWeg2Ndb2PQZspaXMqkzdndTHZnvyHSruDwRrvoLcp_pfg5V5ggkcM0DebYAcddg2jzTQrzb1ZSfSzu1LHdoDuN_trMsRP-ja5qQ</recordid><startdate>20231101</startdate><enddate>20231101</enddate><creator>van de Griendt, Jolande M T M</creator><creator>van den Berg, Nelleke M E</creator><creator>Verdellen, Cara W J</creator><creator>Cath, Daniëlle C</creator><creator>Verbraak, Marc J P M</creator><general>MDPI AG</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9653-0935</orcidid></search><sort><creationdate>20231101</creationdate><title>Working Mechanisms of Exposure and Response Prevention in the Treatment of Tourette Syndrome and Tic Disorders Revisited: No Evidence for within-Session Habituation to Premonitory Urges</title><author>van de Griendt, Jolande M T M ; 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Using a data-driven approach, within-session habituation to premonitory urge intensity was investigated. In total, 29 TS patients rated urge intensity at seven timepoints during ten 1 h ERP sessions.
Latent growth modeling showed an increase in urge intensity during the first 15 min of each session followed by a plateau in the remaining 45 min of the session. This does not support the idea of within-session habituation to premonitory urges as a working mechanism of ERP. Other potential underlying working mechanisms are discussed and should be tested in future research.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>38002700</pmid><doi>10.3390/jcm12227087</doi><orcidid>https://orcid.org/0000-0001-9653-0935</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Age Anxiety Behavior modification Care and treatment Clinical medicine Enterprise resource planning Hypotheses Patients Prevention Tourette syndrome Tourette's syndrome |
| title | Working Mechanisms of Exposure and Response Prevention in the Treatment of Tourette Syndrome and Tic Disorders Revisited: No Evidence for within-Session Habituation to Premonitory Urges |
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